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Kyowa Kirin Announce Symposium, Acceptance of Abstract for Presentation at American Academy of Dermatology 2024 Meeting | ||||||||||
By: PR Newswire Association LLC. - 14 Feb 2024 | Back to overview list |
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PRINCETON, N.J. and TOKYO, Feb. 14, 2024 /PRNewswire/ -- Kyowa Kirin Co., Ltd. (TSE: 4151) today announced that disease education and data from the Phase 2b study of rocatinlimab (AMG451/KHK4083), an investigational product being studied in patients with moderate-to-severe atopic dermatitis, will be presented at the upcoming American Academy of Dermatology (AAD) 2024 Annual Meeting in San Diego from March 8-12, 2024. Atopic Dermatitis (AD), a chronic, heterogeneous, inflammatory disease characterized by skin redness, pruritus, and pain, is driven by skin barrier disruption and T cell–dependent inflammatory pathways; the relative contribution of different inflammatory pathways in driving disease can vary across populations and within individuals over time. Globally, the prevalence of AD is up to 10% among adults and up to 20% among children, making it the 15th most common non-fatal disease and the skin disorder with the highest disease burden, in terms of disability-adjusted life-years. Despite available therapies, many patients with moderate-to-severe AD fail to achieve or sustain treatment goals and/or may not be suitable for or tolerate these therapies. Thus, there remains a need for therapeutic options that can deliver durable benefits across a heterogeneous AD patient population. AD is associated with a significant clinical burden due to unpredictable flares (acute worsening of symptoms) and chronic symptoms, including redness, dryness, and lichenification (skin thickening); clinical burden may be more prominent for those with moderate-to-severe disease. Drs Chih-ho Hong and Raj Chovatiya will highlight data on the heterogeneity of atopic dermatitis and the role of T cells and OX40 signaling in disease pathogenesis.
Date: Saturday, March 9 e-Poster Title: Rocatinlimab Significantly Improves Clinical Responses in Patients with Moderate-To-Severe Atopic Dermatitis by Week 2 in a Randomized Double-Blind Placebo-Controlled Phase 2b Study Author: Emma Guttman- Yassky, MD, PhD About rocatinlimab Amgen and Kyowa Kirin Collaboration About Kyowa Kirin View original content to download multimedia:https://www.prnewswire.com/news-releases/kyowa-kirin-announce-symposium-acceptance-of-abstract-for-presentation-at-american-academy-of-dermatology-2024-meeting-302061345.html SOURCE Kyowa Kirin |
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