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Translational Research in Oncology (TRIO) Partners With Molecular Templates for First-In-Human Phase I Study for MT-5111 | ||
By: Nasdaq / GlobeNewswire - 25 Apr 2019 | Back to overview list |
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EDMONTON, Alberta, April 25, 2019 (GLOBE NEWSWIRE) -- Translational Research in Oncology (TRIO), a global academic clinical research organization, today announced it has partnered with Molecular Templates (Nasdaq: MTEM) to conduct its First-in-Human study for patients with previously treated advanced HER2-positive solid tumors. This Phase I first-in-human study is an open-label, dose escalation and expansion study of MT-5111 given as monotherapy in subjects with HER2-positive solid tumors. The primary objective of the trial is to evaluate the safety and tolerability and determine the recommended Phase II dose of MT-5111 in subjects with advanced HER2-positive solid tumors. “We are pleased to partner with Molecular Templates to bring their research into the clinical setting”, says Launa Aspeslet, PhD, CEO of TRIO. “Our extensive experience in cancer trials coupled with strong investigator relationships, proven operational expertise and commitment to high-quality data makes TRIO the ideal partner to advance MT-5111.” “The depth of experience in the HER2 space that TRIO can offer due to its academic leadership and scientific committee make them a natural fit to coordinate this trial”, added Dennis Slamon, MD, PhD, TRIO Chairman/Executive Director and Director of Clinical Translational Research at the University of California, Los Angeles Jonsson Comprehensive Cancer Center. “The translational research model is the best path to bringing innovative products, like Molecular Templates’ MT-5111, to the market.” “Molecular Templates is delighted to be partnering with TRIO to conduct a Phase I study for MT-5111,” said Roger Waltzman, MD, Chief Medical Officer of Molecular Templates. “We have seen promising responses with our lead pipeline candidate MT-3724 in DLBCL and we are excited to further leverage the novel mechanism of action of our ETB platform with MT-5111 to potentially benefit patients with HER2 positive cancers including breast and gastric cancers.” About MT-5111 About TRIO About Molecular Templates TRIO Media Inquiries: Molecular Templates Investor Contact: |
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