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Placebo Response Mitigation Strategies & Tools for Optimizing Clinical Trials, Upcoming Webinar Hosted by Xtalks and Syneos Health
By: PR Newswire Association LLC. - 04 Oct 2022Back to overview list

In this free webinar, learn how environmental/modifiable factors in clinical trials can be controlled to minimize placebo response. Attendees will learn how accounting for individual patient psychological traits, expectations, perceptions and beliefs can address interpatient variability in placebo response. The featured speakers will discuss the advantages of using multiple approaches to address the placebo response that are customized to specific clinical study protocols.

TORONTO, Oct. 4, 2022  /PRNewswire-PRWeb/ -- This webinar will review available methods to mitigate the negative impact of the placebo response in clinical trials for therapies for diseases of the central nervous system. The featured speakers will discuss the origin and nature of the placebo response, the advantages and limitations of approaches to address the placebo response in drug development and how complementary solutions offered by Syneos Health® Clinical Surveillance & Training (CST) team and Cognivia® may be used in concert to maximize the benefits to trials.

The speakers will discuss strategies and tools for the management of placebo effects with a view to maximizing the clarity of efficacy signals.

Additionally, material presented will also cover the use of prognostic covariates (Placebell©™ covariates) developed specifically to predict the likelihood of placebo responsiveness of patients participating in a clinical trial. Placebell's AI-powered algorithm calculates a placebo responsiveness score based on a sophisticated assessment of patient psychology, expectations and other factors. The use of patients' psychology provides access to a, so far, unreached set of information so critical in phenomena like placebo response. Applying these prognostic covariates significantly decrease the data variability and consequently improve the statistical analysis reducing the risk of trial failure.

Combining the complementary approaches presented in this webinar would position sponsors for higher chances of success in mitigating the impact of the placebo response in clinical trials.

Register to learn about some of the key factors in mediating placebo response in clinical trials, including various mitigation strategies.

Join Dr. Veeraindar Goli, MD, MBA, DLFAPA, VP, Medical Affairs, Syneos Health; Dr. Luke Koschalka, PsyD, Sr. Clinical Scientist, Clinical Surveillance & Training, Syneos Health; and Dr. Dominique Demolle, PhD, CEO, Cognivia, for the live webinar on Monday, October 24, 2022, at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit Placebo Response Mitigation Strategies & Tools for Optimizing Clinical Trials.


Syneos Health® (Nasdaq:SYNH) is the only fully integrated biopharmaceutical solutions organization purpose-built to accelerate customer success. We lead with a product development mindset, strategically blending clinical development, medical affairs, and commercial capabilities to address modern market realities.

To learn more about how we are Shortening the distance from lab to life®, visit or subscribe to our podcast.


Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit

For information about hosting a webinar visit


Vera Kovacevic

Tel: +1 (416) 977-6555 x371


Media Contact

Vera Kovacevic, Xtalks, +1 (416) 977-6555 x371,



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