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Novel Probiotic Strain Dramatically Reduces Antibiotic Resistance In Infants | ||
By: PR Newswire Association LLC. - 14 Aug 2019 | Back to overview list |
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DAVIS, Calif., Aug. 14, 2019 /PRNewswire/ -- Evolve BioSystems, Inc. today announced findings from a new study that identified healthy, breastfed U.S. infants have alarmingly high levels of antibiotic resistance genes early in life -- and how feeding babies a specific strain of Bifidobacterium -- B. infantis EVC001 -- along with breast milk, lowered the total levels of antibiotic resistance genes in the infant gut microbiome by 90 percent, including a near elimination of bacteria such as Escherichia, Clostridium and Staphylococcus. The paper, published in Antimicrobial Resistance and Infection Control, demonstrates that B. infantis EVC001 (commercially known as Evivo® baby probiotic) works uniquely with breast milk to suppress the growth of potentially pathogenic bacteria that harbor the genes responsible for antibiotic resistance. No other probiotic has demonstrated this benefit. Experience the interactive Multichannel News Release here: https://www.multivu.com/players/English/8588551-evolve-biosystems-probiotic-evivo-strain-antibiotic-resistence/ Milestone in the Fight Against Antibiotic Resistance "Even in scenarios for optimal health where babies are born vaginally, full-term and are breastfed, we're still seeing an increase in antibiotic resistance," said Jae Kim, MD, neonatologist specializing in gastroenterology, hepatology and nutrition and co-author of Best Medicine: Human Milk in the NICU. "Pathogens that harbor antibiotic resistance genes and cause infection can become very hard to treat. However, this particular probiotic bacterium uses a unique mechanism allowing it to create an inhospitable environment for these pathogens. The data clearly show a substantial improvement in the gut microbiome with B. infantis EVC001 in infants who are normally thought of as the healthiest." About the Study
Based on these findings, and the potential for B. infantis EVC001 to greatly impact public health, Evolve BioSystems has joined the AMR Challenge led by the CDC with a commitment to continue research and development of microbiome-based approaches to reduce antibiotic resistance in infants. These groundbreaking findings follow a recent study published by UC-Davis researchers and the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), which also demonstrated the crucial role Bifidobacterium can play in reducing antimicrobial resistance genes. In light of these breakthroughs, scientists are optimistic that increasing the abundance of Bifidobacterium in the infant gut is an effective tactic in the fight against antibiotic resistance. "Feeding B. infantis EVC001 to babies is the first effective approach shown to decrease antibiotic resistance genes in the infant gut microbiome," said Dr. Casaburi. "Our data further support recent studies that link breastfeeding to a reduction of antibiotic resistance in infants, as we show here that B. infantis works directly with human breast milk to reduce the abundance of pathogens that carry antibiotic resistance genes in the infant gut." About Evolve BioSystems 1 https://www.cdc.gov/drugresistance/about.html Contact
View original content:http://www.prnewswire.com/news-releases/novel-probiotic-strain-dramatically-reduces-antibiotic-resistance-in-infants-300901307.html SOURCE Evolve BioSystems, Inc. |
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Copyright 2019 PR Newswire Association LLC. | Back to overview list |